Information flow in the rat thalamo-cortical system: spontaneous vs. stimulus-evoked activities.

ABSTRACT: The interaction between the thalamus and sensory cortex plays critical roles in sensory processing. Previous studies have revealed pathway-specific synaptic properties of thalamo-cortical connections. However, few studies to date have investigated how each pathway routes moment-to-moment information. Here, we simultaneously recorded neural activity in the auditory thalamus (or ventral division of the medial geniculate body; MGv) and primary auditory cortex (A1) with a laminar resolution in anesthetized rats. Transfer entropy (TE) was used as an information theoretic measure to operationalize "information flow". Our analyses confirmed that communication between the thalamus and cortex was strengthened during presentation of auditory stimuli. In the resting state, thalamo-cortical communicat

SUBMITTER: Ishizu K 

PROVIDER: S-EPMC8479136 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature