Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom.

ABSTRACT: The COVID-19 pandemic has resulted in unprecedented challenges for healthcare systems worldwide. It has also stimulated research in a wide range of areas including rapid diagnostics, novel therapeutics, use of technology to track patients and vaccine development. Here, we describe our experience of rapidly setting up and delivering a novel COVID-19 vaccine trial, using clinical and research staff and facilities in three National Health Service Trusts in Cambridgeshire, United Kingdom. We encountered and overcame a number of challenges including differences in organisational structures, research facilities available, staff experience and skills, information technology and communications infrastructure, and research training and assessment procedures. We overcame these by setting up a projec

SUBMITTER: Torok ME 

PROVIDER: S-EPMC8479147 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature