COVID-19 patients and Dementia: Frontal cortex transcriptomic data.

ABSTRACT: Since the association of SARS-Cov-2 infection with Nervous System (NS) manifestations, we performed RNA-sequencing analysis in Frontal Cortex of COVID-19 positive or negative individuals and affected or not by Dementia individuals. We examined gene expression differences in individuals with COVID-19 and Dementia compared to Dementia only patients by collecting transcript counts in each sample and performing Differential Expression analysis. We found eleven genes satisfying our significance criteria, all of them being protein coding genes. These data are suitable for integration with supplemental samples and for analysis according to different individuals' classification. Also, differential expression evaluation may be implemented with other scientific purposes, such as research of unannota

SUBMITTER: Garofalo M 

PROVIDER: S-EPMC8479506 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature