Bridging large-scale cortical networks: Integrative and function-specific hubs in the thalamus.

ABSTRACT: The thalamus is critical for the brain's integrative hub functions; however, the localization and characterization of the different thalamic hubs remain unclear. Using a voxel-level network measure called functional connectivity overlap ratio (FCOR), we examined the thalamus' association with large-scale resting-state networks (RSNs) to elucidate its connector hub roles. Connections to the core-neurocognitive networks were localized in the anterior and medial parts, such as the anteroventral and mediodorsal nuclei areas. Regions functionally connected to the sensorimotor network were distinctively located around the lateral pulvinar nucleus but to a limited extent. Prominent connector hubs include the anteroventral, ventral lateral, and mediodorsal nuclei with functional connections to mul

SUBMITTER: Kawabata K 

PROVIDER: S-EPMC8479782 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature