Enzymology and Regulation of δ¹-Pyrroline-5-Carboxylate Synthetase 2 From Rice.

ABSTRACT: Under several stress conditions, such as excess salt and drought, many plants accumulate proline inside the cell, which is believed to help counteracting the adverse effects of low water potential. This increase mainly relies upon transcriptional induction of δ¹-pyrroline-5-carboxylate synthetase (P5CS), the enzyme that catalyzes the first two steps in proline biosynthesis from glutamate. P5CS mediates both the phosphorylation of glutamate and the reduction of γ-glutamylphosphate to glutamate-5-semialdehyde, which spontaneously cyclizes to δ¹-pyrroline-5-carboxylate (P5C). In most higher plants, two isoforms of P5CS have been found, one constitutively expressed to satisfy proline demand for protein synthesis, the other stress-induced. Despite the number of papers to i

SUBMITTER: Sabbioni G 

PROVIDER: S-EPMC8480329 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature