Predictors of poor prognosis in healthy, young, individuals with SARS-CoV-2 infections.

ABSTRACT:

Objectives

To identify predictors of poor prognosis in previously healthy young individuals admitted to hospital with coronavirus disease 2019 (COVID-19).

Methods

We studied a cohort of patients hospitalized with COVID-19. All patients without co-morbidities, without usual treatments and ≤65 years old were selected from an international registry (HOPE-COVID-19, NCT04334291). We focused on baseline variables-symptoms and signs at admission-to analyse risk factors for poor prognosis. The primary end point was a composite of major adverse clinical events during hospitalization including mortality, mechanical ventilation, high-flow nasal oxygen therapy, prone, sepsis, systemic inflammatory response syndrome and embolic events.

Results

Overall, 773 healthy young patients w

SUBMITTER: Espejo-Paeres C 

PROVIDER: S-EPMC8481119 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature