Health-related quality of life in patients with autoimmune hepatitis.

ABSTRACT:

Background

Autoimmune hepatitis (AIH) is a rare chronic liver disease. Impaired health-related quality of life (HRQL) contributes to the overall disease burden. At current, only limited data related to the impact of treatment response on HRQL are available.

Objective

The aim of the study was to determine the impact of biochemical remission on HRQL.

Methods

Patients with AIH were prospectively enrolled between July 2018 and June 2019. A liver disease-specific tool, the chronic liver disease questionnaire (CLDQ) and the generic EQ-5D-5L were used to quantify HRQL. Treatment response was assessed biochemically by measurement of immunoglobulin G, ALT and AST. The cohort was divided into two groups according to their biochemical remission status in either complete vs. inco

SUBMITTER: Michel M 

PROVIDER: S-EPMC8481193 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature