Ontology highlight
ABSTRACT:
SUBMITTER: Sobah ML
PROVIDER: S-EPMC8481645 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Sobah Mohamed Luban ML Liongue Clifford C Ward Alister C AC
Frontiers in medicine 20210916
Cytokine signaling represents one of the cornerstones of the immune system, mediating the complex responses required to facilitate appropriate immune cell development and function that supports robust immunity. It is crucial that these signals be tightly regulated, with dysregulation underpinning immune defects, including excessive inflammation, as well as contributing to various immune-related malignancies. A specialized family of proteins called suppressors of cytokine signaling (SOCS) partici ...[more]