Experiences and Perspectives From Women Taking Investigational Therapy for Hepatitis C Virus During Pregnancy.

ABSTRACT:

Objective

Describe the experiences and perspectives among pregnant people with chronic HCV infection receiving ledipasvir/sofosbuvir (LDV/SOF) therapy during pregnancy.

Methods

We conducted semi-structured, in-depth interviews within an open-label, phase 1 study of LDV/SOF therapy among pregnant people with chronic HCV infection. Participants took 12 weeks of LDV/SOF and were interviewed at enrollment and again at the end of treatment. We transcribed the interviews verbatim and coded them with NVivo software for subsequent inductive thematic analysis.

Results

Nine pregnant people completed the study, leading to 18 interview transcripts. All participants identified as women. Eight women acquired HCV through injection drug use, and 1 through perinatal transmission. We i

SUBMITTER: Kislovskiy Y 

PROVIDER: S-EPMC8481705 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature