Characterization of Outcomes by Surgical Management of Lung Neuroendocrine Tumors Associated With Cushing Syndrome.

ABSTRACT:

Importance

Ectopic adrenocorticotropic hormone secretion from lung tumors causing Cushing syndrome are associated with high rates of morbidity. Optimal management remains obscure because knowledge is based on rare reports with few patients.

Objective

To characterize the outcomes of lung neuroendocrine tumors associated with Cushing syndrome.

Design, setting, and participants

An observational case series review from 1982 to 2020 was conducted in a single institution referral center. Kaplan-Meier analysis estimated disease-free survival (DFS). Participants underwent curative-intent surgery for a lung neuroendocrine tumor causing Cushing syndrome.

Exposures

Lobectomy or pneumonectomy vs sublobar resection.

Main outcomes and measures

Disease-free survival, d

SUBMITTER: Seastedt KP 

PROVIDER: S-EPMC8482056 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature