Differential Expression of Non-Coding RNA Signatures in Thyroid Cancer between Two Ethnic Groups.

ABSTRACT: Filipino Americans show higher thyroid cancer recurrence rates compared to European Americans. Although they are likely to die of this malignancy, the molecular mechanism has not yet been determined. Recent studies demonstrated that small non-coding RNAs could be utilized to assess thyroid cancer prognosis in tumor models. The goal of this study is to determine whether microRNA (miRNA) signatures are differentially expressed in thyroid cancer in two different ethnic groups. We also determined whether these miRNA signatures are related to cancer staging. This is a retrospective study of archival samples from patients with thyroid cancer (both sexes) in the pathology division from the last ten years at Loma Linda University School of Medicine, California. Deidentified patient demographics we

SUBMITTER: Rood K 

PROVIDER: S-EPMC8482137 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature