Stimuli-Responsive Nanoplatform-Assisted Photodynamic Therapy Against Bacterial Infections.

ABSTRACT: Bacterial infections are common diseases causing tremendous deaths in clinical settings. It has been a big challenge to human beings because of the antibiotics abuse and the newly emerging microbes. Photodynamic therapy (PDT) is a reactive oxygen species-based therapeutic technique through light-activated photosensitizer (PS). Recent studies have highlighted the potential of PDT as an alternative method of antibacterial treatment for its broad applicability and high efficiency. However, there are some shortcomings due to the low selectivity and specificity of PS. Growing evidence has shown that drug delivery nanoplatforms have unique advantages in enhancing therapeutic efficacy of drugs. Particularly, stimuli-responsive nanoplatforms, as a promising delivery system, provide great opportuni

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC8482315 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature