Pre-implant left ventricular dimension is not associated with worse outcomes after left ventricular assist device implantation.

ABSTRACT:

Background

Left ventricular dimension has the potential to impact clinical outcomes following implantation of left ventricular assist devices (LVAD). We investigated the effect of pre-implant left ventricular end-diastolic diameter (LVEDD) on outcomes following LVAD implantation.

Methods

Patients implanted with a continuous-flow LVAD between 2004 and 2018 at a single institution were included. The primary outcome was death while on LVAD support. Secondary outcomes included adverse event rates such as renal failure requiring dialysis, device thrombosis, and right ventricular failure. The LVEDD measurements were dichotomized using restricted cubic splines and threshold regression. Survival was determined using Kaplan-Meier estimates. Multivariable logistic regression was used

SUBMITTER: Srinivasan AJ 

PROVIDER: S-EPMC8482326 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature