Ontology highlight
ABSTRACT:
SUBMITTER: Chaudhary S
PROVIDER: S-EPMC8482365 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Chaudhary Surbhi S Patidar Anil A Dhiman Asmita A Chaubey Gaurav Kumar GK Dilawari Rahul R Talukdar Sharmila S Modanwal Radheshyam R Raje Manoj M
Cell death & disease 20210930 10
Rapid clearance of apoptotic cells by phagocytes is crucial for organogenesis, tissue homeostasis, and resolution of inflammation. This process is initiated by surface exposure of various 'eat me' ligands. Though phosphatidylserine (PS) is the best recognized general recognition ligand till date, recent studies have shown that PS by itself is not sufficient for clearance of apoptotic cells. In this study, we have identified a specific pleioform of GAPDH (Glyceraldehyde 3-phosphate dehydrogenase) ...[more]