Prevalence of dry eye in patients with systemic lupus erythematosus: a meta-analysis.

ABSTRACT:

Objectives

To investigate dry eye disease (DED) in patients affected by systemic lupus erythematosus (SLE).

Methods

We conducted a systematic search of the literature on PubMed, EMBASE and the Cochrane Library databases from conception to 30 April 2020 for studies related to dry eye, secondary Sjögren's syndrome (sSS) and SLE. Original full-text articles with the number of patients diagnosed with SLE of over 15 were included. The risk of bias was evaluated with a validated critical appraisal tool which assessed study quality based on confounding factors, selection bias, bias related to measurement and bias related to data analysis. Data were extracted and pooled to evaluate the overall prevalence of DED with the random-effect model and sSS with the fixed effect model.

Res

SUBMITTER: Wang L 

PROVIDER: S-EPMC8483036 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature