Association between systemic sclerosis and peripheral arterial disease: a nationwide observation retrospective claim records cohort study in Taiwan.

ABSTRACT:

Objectives

Recent studies have proposed associations between systemic sclerosis (SSc) and atherosclerosis and between SSc and cardiovascular disease. However, in Asia, no large-scale studies have focused on the association between peripheral arterial disease (PAD) and SSc.

Setting

A nationwide observation retrospective cohort study.

Participants

The National Health Insurance Research Database was used for selecting patients diagnosed with SSc from 2000 to 2011. Patients diagnosed with PAD before the index date were excluded.

Primary and secondary outcome measures

The SSc cohort comprised 1106 patients with SSc, and the non-SSc cohort comprised 4424 matched controls. The Cox proportional hazards regression model was used for analysing the adjusted risk of PAD be

SUBMITTER: Hsieh MC 

PROVIDER: S-EPMC8483053 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature