Outcome measures used in trials on gait rehabilitation in multiple sclerosis: A systematic literature review.

ABSTRACT:

Background

Multiple Sclerosis (MS) is associated with impaired gait and a growing number of clinical trials have investigated efficacy of various interventions. Choice of outcome measures is crucial in determining efficiency of interventions. However, it remains unclear whether there is consensus on which outcome measures to use in gait intervention studies in MS.

Objective

We aimed to identify the commonly selected outcome measures in randomized controlled trials (RCTs) on gait rehabilitation interventions in people with MS. Additional aims were to identify which of the domains of the International Classification of Functioning, Disability and Health (ICF) are the most studied and to characterize how outcome measures are combined and adapted to MS severity.

Methods

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SUBMITTER: Santisteban L 

PROVIDER: S-EPMC8483298 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature