Donor Characteristics and Recipient Outcomes After Heart Transplantation in Adult Congenital Heart Disease.

ABSTRACT: Background Patients with adult congenital heart disease (ACHD) experience long waitlist times for heart transplantation (HTx) while a large proportion of donor hearts are refused. The goal of this study was to inform optimal donor selection for patients with ACHD listed for HTx by examining the impact of donor characteristics on post-HTx outcomes. Methods and Results Using the Scientific Registry of Transplant Recipients, we conducted a retrospective analysis of patients aged ≥18 years listed for HTx in the United States between 2000 and 2016. We compared waitlist times between patients with ACHD and patients with noncongenital heart disease and constructed multivariate hazard models to identify donor characteristics associated with increased waitlist time. We then compared post-HTx surviv

SUBMITTER: Huntley GD 

PROVIDER: S-EPMC8483491 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature