Perspective: Milk microRNAs as Important Players in Infant Physiology and Development.

ABSTRACT: Evolutionary selective pressure on lactation has resulted in milk that provides far more than simply essential nutrients, delivering a complex repertoire of agents from hormones to intact cells. Human infants are born with low barrier integrity of their gut, which means that many of the complex biopolymer components of milk enter and circulate in lymph and blood, reaching organs throughout the body. Due to this state of gut maturation, all components of milk are potentially part of the crosstalk between mother and infants. This article highlights the functions of milk's complex biopolymers, more specifically the potential role of microRNAs (miRNAs) contained in extracellular vesicles in human milk. miRNAs are key effectors in the regulation of many biological processes during early-age dev

SUBMITTER: Leroux C 

PROVIDER: S-EPMC8483967 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature