Efficacy and Safety of Platelet-Rich Plasma in Melasma: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Melasma is a chronic and recurrent skin problem for which an effective therapy is currently lacking. Platelet-rich plasma (PRP) has recently emerged as a novel treatment for melasma, but to date there has been no systematic evaluation of its efficacy and safety.

Methods

The Web of Science, PubMed, EMBASE, China National Knowledge Infrastructure (CNKI) and the Cochrane Library databases were searched for relevant articles using the search items "melasma," "chloasma" and "platelet-rich plasma." STATA version 15.1 software was used to analyze data. Study outcomes were calculated using standardized mean differences with 95% confidence intervals (CIs).

Results

The database search identified ten studies involving 395 adult patients that met the inclusion criter

SUBMITTER: Zhao L 

PROVIDER: S-EPMC8484406 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature