The virucidal effects of 405 nm visible light on SARS-CoV-2 and influenza A virus.

ABSTRACT: The germicidal potential of specific wavelengths within the electromagnetic spectrum is an area of growing interest. While ultra-violet (UV) based technologies have shown satisfactory virucidal potential, the photo-toxicity in humans coupled with UV associated polymer degradation limit their use in occupied spaces. Alternatively, longer wavelengths with less irradiation energy such as visible light (405 nm) have largely been explored in the context of bactericidal and fungicidal applications. Such studies indicated that 405 nm mediated inactivation is caused by the absorbance of porphyrins within the organism creating reactive oxygen species which result in free radical damage to its DNA and disruption of cellular functions. The virucidal potential of visible-light based technologies has b

SUBMITTER: Rathnasinghe R 

PROVIDER: S-EPMC8484654 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature