Between virus correlations in the outcome of infection across host species: Evidence of virus by host species interactions.

ABSTRACT: Virus host shifts are a major source of outbreaks and emerging infectious diseases, and predicting the outcome of novel host and virus interactions remains a key challenge for virus research. The evolutionary relationships between host species can explain variation in transmission rates, virulence, and virus community composition between hosts, but it is unclear if correlations exist between related viruses in infection traits across novel hosts. Here, we measure correlations in viral load of four Cripavirus isolates across experimental infections of 45 Drosophilidae host species. We find positive correlations between every pair of viruses tested, suggesting that some host clades show broad susceptibility and could act as reservoirs and donors for certain types of viruses. Ad

SUBMITTER: Imrie RM 

PROVIDER: S-EPMC8484721 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature