Sex Differences in Cardiac Troponin I and T and the Prediction of Cardiovascular Events in the General Population.

ABSTRACT:

Background

Cardiac troponin concentrations differ in women and men, but how this influences risk prediction and whether a sex-specific approach is required is unclear. We evaluated whether sex influences the predictive ability of cardiac troponin I and T for cardiovascular events in the general population.

Methods

High-sensitivity cardiac troponin (hs-cTn) I and T were measured in the Generation Scotland Scottish Family Health Study of randomly selected volunteers drawn from the general population between 2006 and 2011. Cox-regression models evaluated associations between hs-cTnI and hs-cTnT and the primary outcome of cardiovascular death, myocardial infarction, or stroke.

Results

In 19 501 (58% women, mean age 47 years) participants, the primary outcome occurred in 2

SUBMITTER: Kimenai DM 

PROVIDER: S-EPMC8486023 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature