Ontology highlight
ABSTRACT:
SUBMITTER: Mahmoud RH
PROVIDER: S-EPMC8486749 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Mahmoud Ramez H RH Biguetti Claudia C CC Simionato Gustavo B GB Custódio Isabela C IC Silva Raquel B P RBP Duarte Marco A H MAH Faverani Leonardo P LP Ervolino Edilson E Fakhouri Walid D WD Matsumoto Mariza A MA
Scientific reports 20211001 1
This study investigated the role 5-lypoxigenase (5-LO) on alveolar socket healing in aged female mice treated with zoledronic acid (ZL). Forty 129/Sv female mice (64-68 weeks old), 20 wild type (WT) and 20 5-LO knockout (5LOKO) were equally distributed according to ZL treatment: WT Control, WT ZL, 5LOKO Control, and 5LOKO ZL. ZL groups were treated with an intraperitoneal injection of 250 µg/Kg of ZL, while controls were treated with saline. Treatments were administered once a week, starting fou ...[more]