Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior.

ABSTRACT: The gut microbiome has been speculated to modulate feeding behavior through multiple factors, including short-chain fatty acids (SCFA). Evidence on this relationship in humans is however lacking. We aimed to explore if specific bacterial genera relate to eating behavior, diet, and SCFA in adults. Moreover, we tested whether eating-related microbiota relate to treatment success in patients after Roux-en-Y gastric bypass (RYGB). Anthropometrics, dietary fiber intake, eating behavior, 16S-rRNA-derived microbiota, and fecal and serum SCFA were correlated in young overweight adults (n = 27 (9 F), 21-36 years, BMI 25-31 kg/m²). Correlated genera were compared in RYGB (n = 23 (16 F), 41-70 years, BMI 25-62 kg/m²) and control patients (n = 17 (11 F), 26-69 years, BMI 25-48 kg

SUBMITTER: Medawar E 

PROVIDER: S-EPMC8486801 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature