Central sensitization, illness perception and obesity should be considered when interpreting disease activity in axial spondyloarthritis.

ABSTRACT:

Objectives

Many patients with axial spondyloarthritis (axSpA) report persistent pain even when treated with anti-inflammatory agents. Our aim was to explore the presence of central sensitization (CS) and different types of illness perceptions in patients with axSpA, and to assess their associations with disease activity assessments.

Methods

Consecutive outpatients from the Groningen Leeuwarden Axial Spondyloarthritis (GLAS) cohort were included. Besides standardized assessments, patients filled out the Central Sensitization Inventory (CSI), Illness Perception Questionnaire (IPQ-R) and Pain Catastrophizing Scale (PCS). Univariable and multivariable linear regression analyses were used to investigate the association between questionnaire scores, patient characteristics and dis

SUBMITTER: Kieskamp SC 

PROVIDER: S-EPMC8487271 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature