Handgrip strength to predict extubation outcome: a prospective multicenter trial.

ABSTRACT:

Background

ICU-acquired weakness (ICUAW) has been shown to be associated with prolonged duration of mechanical ventilation and extubation failure. It is usually assessed through Medical Research Council (MRC) score, a time-consuming score performed by physiotherapists. Handgrip strength (HG) can be monitored very easily at the bedside. It has been shown to be a reproducible and reliable marker of global muscular strength in critical care patients. We sought to test if muscular weakness, as assessed by handgrip strength, was associated with extubation outcome.

Methods

Prospective multicenter trial over an 18 months period in six mixed ICUs. Adults receiving mechanical ventilation for at least 48 h were eligible. Just before weaning trial, HG, Maximal Inspiratory Pressure (MIP

SUBMITTER: Cottereau G 

PROVIDER: S-EPMC8487340 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature