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Genetic diversity of SARS-CoV-2 in South America: demographic history and structuration signals.


ABSTRACT: In 2020, the emergence of SARS-CoV-2 caused a global public health crisis with significant mortality rates and a large socioeconomic burden. The rapid spread of this new virus has led to the appearance of new variants, making the characterization and monitoring of genetic diversity necessary to understand the population dynamics and evolution of the virus. Here, a population-genetics-based study was performed starting with South American genome sequences available in the GISAID database to investigate the genetic diversity of SARS-CoV-2 on this continent and the evolutionary mechanisms that modulate it.

SUBMITTER: Buitrago SP 

PROVIDER: S-EPMC8487618 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Genetic diversity of SARS-CoV-2 in South America: demographic history and structuration signals.

Buitrago Sindy P SP   Garzón-Ospina Diego D  

Archives of virology 20211003 12


In 2020, the emergence of SARS-CoV-2 caused a global public health crisis with significant mortality rates and a large socioeconomic burden. The rapid spread of this new virus has led to the appearance of new variants, making the characterization and monitoring of genetic diversity necessary to understand the population dynamics and evolution of the virus. Here, a population-genetics-based study was performed starting with South American genome sequences available in the GISAID database to inves  ...[more]

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