Childhood Sjogren syndrome: features of an international cohort and application of the 2016 ACR/EULAR classification criteria.

ABSTRACT:

Objective

Sjögren syndrome in children is a poorly understood autoimmune disease. We aimed to describe the clinical and diagnostic features of children diagnosed with Sjögren syndrome and explore how the 2016 ACR/EULAR classification criteria apply to this population.

Methods

An international workgroup retrospectively collected cases of Sjögren syndrome diagnosed under 18 years of age from 23 centres across eight nations. We analysed patterns of symptoms, diagnostic workup, and applied the 2016 ACR/EULAR classification criteria.

Results

We identified 300 children with Sjögren syndrome. The majority of patients n = 232 (77%) did not meet 2016 ACR/EULAR classification criteria, but n = 110 (37%) did not have sufficient testing done to even possibly achieve the score nec

SUBMITTER: Basiaga ML 

PROVIDER: S-EPMC8487648 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature