Associations of trauma and posttraumatic stress disorder with aldosterone in women.

ABSTRACT:

Background

Posttraumatic stress disorder (PTSD) has been associated with increased cardiovascular risk, however, underlying mechanisms have not been fully specified. PTSD is associated with stress-related hormones, including dysregulated glucocorticoid activity. Dysregulation of aldosterone, a mineralocorticoid activated by psychological stress and implicated in cardiovascular damage, may be a relevant pathway linking PTSD and cardiovascular risk. Few studies to date have evaluated the association between PTSD and aldosterone, none with repeated measures of aldosterone. We examined if trauma and PTSD were associated with altered aldosterone levels relative to women unexposed to trauma.

Methods

The association of trauma exposure and chronic PTSD with plasma aldosterone levels

SUBMITTER: Nishimi K 

PROVIDER: S-EPMC8487934 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature