Antibiotics in the pipeline: a literature review (2017-2020).

ABSTRACT:

Introduction

Antimicrobial resistance (AMR) is an emerging global threat. It increases mortality and morbidity and strains healthcare systems. Health care professionals can counter the rising AMR by promoting antibiotic stewardship and facilitating new drug development. Even with the economic and scientific challenges, it is reassuring that new agents continue to be developed.

Methods

This review addresses new antibiotics in the pipeline. We conducted a review of the literature including Medline, Clinicaltrials.org, and relevant pharmaceutical companies for approved and in pipeline antibiotics in phase 3 or new drug application (NDA).

Results

We found a number of new antibiotics and reviewed their current development status, mode of action, spectra of activity, and in

SUBMITTER: Al-Tawfiq JA 

PROVIDER: S-EPMC8488069 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature