Comparison of ⁶⁸Ga-labeled Prostate-specific Membrane Antigen Ligand Positron Emission Tomography/Magnetic Resonance Imaging and Positron Emission Tomography/Computed Tomography for Primary Staging of Prostate Cancer: A Systematic Review and Meta-analysis.

ABSTRACT:

Context

In December 2020, the US Food and Drug Administration approved a ⁶⁸Ga-labeled prostate-specific membrane antigen ligand (⁶⁸Ga-PSMA-11) for positron emission tomography (PET) in patients with suspected prostate cancer (PCa) metastasis who are candidates for initial definitive therapy. ⁶⁸Ga-PSMA PET is increasingly performed for these patients and is usually combined with computed tomography (CT). In recent years, ⁶⁸Ga-PSMA PET has been combined with high-resolution magnetic resonance imaging (MRI), which is beneficial for T staging and may further enhance the staging of primary PCa.

Objective

To compare the diagnostic accuracy of ⁶⁸Ga-PSMA PET/MRI with ⁶⁸Ga-PSMA PET/CT for staging of primary PCa.

Evi

SUBMITTER: Ling SW 

PROVIDER: S-EPMC8488242 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature