Protein music of enhanced musicality by music style guided exploration of diverse amino acid properties.

ABSTRACT: Inspired by the traceable analogies between protein sequences and music notes, protein music has been composed from amino acid sequences for popularizing science and sourcing melodies. Despite the continuous development of protein-to-music algorithms, the musicality of protein music lags far behind human music. Musicality may be enhanced by fine-tuned protein-to-music mapping to the features of a specific music style. We analyzed the features of a music style (Fantasy-Impromptu style), and used the quantized musical features to guide broad exploration of diverse amino acid properties (104 properties, sequence patterns and variations) for developing a novel protein-to-music algorithm of enhanced musicality. This algorithm was applied to 18 proteins of various biological functions. The deriv

SUBMITTER: Tay NW 

PROVIDER: S-EPMC8488493 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature