A prospective study of dietary flavonoid intake and risk of glioma in US men and women.

ABSTRACT:

Background

Flavonoids are a diverse group of plant constituents with demonstrated neuroprotective and anti-tumor effects. Flavonoid intake may decrease the risk of glioma, but the possibility of an association has not yet been investigated in humans.

Objectives

We evaluated the association between dietary flavonoid consumption and the risk of glioma.

Methods

We followed participants in the female Nurses' Health Study (1984-2014; n = 81,688) and Nurses' Health Study II (1991-2017; n = 95,228) and the male Health Professionals Follow-Up Study (1986-2014; n = 49,885). We used multivariable-adjusted Cox proportional hazards regression models to evaluate the associations between average long-term (up to 30 years) or recent (up to 12 years) dietary flavonoid intake (total f

SUBMITTER: Bever AM 

PROVIDER: S-EPMC8488865 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature