Determinants of fatty acid content and composition of human milk fed to infants born weighing <1250 g.

ABSTRACT:

Background

Infants born at very low birth weight (VLBW) are vulnerable to deficits in fatty acids (FAs) but little is known of factors that influence the intakes or composition of their human milk feeds.

Objectives

We aimed to identify sources of variability in the fat composition of human milk fed to VLBW infants and examine the impact of milk source (mother's own or donor) on fat and FA intakes.

Methods

Serial samples of mother's milk (n = 476) and donor milk (n = 53) fed to infants born weighing <1250 g (n = 114 infants from 100 mothers) were collected [Optimizing Mothers' Milk for Preterm Infants (OptiMoM) randomized clinical trial]. Fat and FA were analyzed using a mid-infrared human milk analyzer and GC with flame ionization detection.

Results

At full ent

SUBMITTER: Hopperton KE 

PROVIDER: S-EPMC8488876 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature