MEYE: Web App for Translational and Real-Time Pupillometry.

ABSTRACT: Pupil dynamics alterations have been found in patients affected by a variety of neuropsychiatric conditions, including autism. Studies in mouse models have used pupillometry for phenotypic assessment and as a proxy for arousal. Both in mice and humans, pupillometry is noninvasive and allows for longitudinal experiments supporting temporal specificity; however, its measure requires dedicated setups. Here, we introduce a convolutional neural network that performs online pupillometry in both mice and humans in a web app format. This solution dramatically simplifies the usage of the tool for the nonspecialist and nontechnical operators. Because a modern web browser is the only software requirement, this choice is of great interest given its easy deployment and setup time reduction. The tested

SUBMITTER: Mazziotti R 

PROVIDER: S-EPMC8489024 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature