The effect of ArcA on the growth, motility, biofilm formation, and virulence of Plesiomonas shigelloides.

ABSTRACT:

Background

The anoxic redox control binary system plays an important role in the response to oxygen as a signal in the environment. In particular, phosphorylated ArcA, as a global transcription factor, binds to the promoter regions of its target genes to regulate the expression of aerobic and anaerobic metabolism genes. However, the function of ArcA in Plesiomonas shigelloides is unknown.

Results

In the present study, P. shigelloides was used as the research object. The differences in growth, motility, biofilm formation, and virulence between the WT strain and the ΔarcA isogenic deletion mutant strain were compared. The data showed that the absence of arcA not only caused growth retardation of P. shigelloides in the log phase, but also greatly reduced the glucose utilization

SUBMITTER: Yan J 

PROVIDER: S-EPMC8489083 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature