Intraluminal thrombus: Innocent bystander or factor in abdominal aortic aneurysm pathogenesis?

ABSTRACT:

Background

Abdominal aortic aneurysms (AAAs) represent a complex multifactorial hemodynamic, thrombotic, and inflammatory process that can ultimately result in aortic rupture and death. Despite improved screening and surgical management of AAAs, the mortality rates have remained high after rupture, and little progress has occurred in the development of nonoperative treatments. Intraluminal thrombus (ILT) is present in most AAAs and might be involved in AAA pathogenesis. The present review examined the latest clinical and experimental evidence for possible involvement of the ILT in AAA growth and rupture.

Methods

A literature review was performed after a search of the PubMed database from 2012 to June 2020 using the terms "abdominal aortic aneurysm" and "intraluminal thrombus

SUBMITTER: Boyd AJ 

PROVIDER: S-EPMC8489244 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature