Chilblains during lockdown are associated with household exposure to SARS-CoV-2: a multicentre case-control study.

ABSTRACT:

Objectives

During the COVID-19 pandemic, numerous cases of chilblains have been reported. However, in most cases, RT-PCR or serology did not confirm SARS-CoV-2 infection. Hypotheses have been raised about an interferon-mediated immunological response to SARS-CoV-2, leading to effective clearance of the SARS-CoV-2 without the involvement of humoral immunity. Our objective was to explore the association between chilblains and exposure to SARS-CoV-2.

Methods

In this multicentre case-control study, cases were the 102 individuals referred to five referral hospitals for chilblains occurring during the first lockdown (March to May 2020). Controls were recruited from healthy volunteers' files held by the same hospitals. All members of their households were included, resulting in 77

SUBMITTER: Poizeau F 

PROVIDER: S-EPMC8489277 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature