Does mRNA SARS-CoV-2 vaccine detrimentally affect male fertility, as reflected by semen analysis?

ABSTRACT:

Research question

Does Pfizer's coronavirus disease 2019 (COVID-19) vaccination detrimentally affect semen analysis parameters?

Design

A prospective cohort study was conducted at a single large tertiary centre in Israel between February and March of 2021. Semen samples from 75 fertile men were analysed 1-2 months following their second dose of Pfizer's COVID-19 vaccine. The semen parameters were compared with the World Health Organization (WHO) reference ranges. The primary outcome was the percentage of abnormal semen parameters in those who were vaccinated, i.e. the rates of oligozoospermia, reduced percentage of motile spermatozoa and abnormal sperm morphology.

Results

The interval from the time of the second vaccination to the date of participation was on average 3

SUBMITTER: Lifshitz D 

PROVIDER: S-EPMC8489287 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature