High Contrast Ultrasonic Method With Multi-Spatiotemporal Compounding for Monitoring Catheter-Based Ultrasound Thermal Therapy: Development and Ex Vivo Evaluations.

ABSTRACT:

Objective

Changes in ultrasound backscatter energy (CBE) imaging can monitor thermal therapy. Catheter-based ultrasound (CBUS) can treat deep tumors with precise spatial control of energy deposition and ablation zones, of which CBE estimation can be limited by low contrast and robustness due to small or inconsistent changes in ultrasound data. This study develops a multi-spatiotemporal compounding CBE (MST-CBE) imaging approach for monitoring specific to CBUS thermal therapy.

Methods

Ex vivo thermal ablations were performed with stereotactic positioning of a 180° directional CBUS applicator, temperature monitoring probes, endorectal US probe, and subsequent lesion sectioning and measurement. Five frames of raw radiofrequency data were acquired throughout in 15s intervals. Us

SUBMITTER: Wang D 

PROVIDER: S-EPMC8489743 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature