Implementation of an Analgesia-Sedation Protocol Is Associated With Reduction in Midazolam Usage in the PICU.

ABSTRACT:

Objectives

Examine the association of a revised analgesia-sedation protocol with midazolam usage in the PICU.

Design

A single-center nonrandomized before-after study.

Setting

PICU at a quaternary pediatric hospital (Boston Children's Hospital, Boston, MA).

Patients

Children admitted to the PICU who were mechanically ventilated for greater than 24 hours. The preimplementation cohort included 190 eligible patients admitted between July 29, 2017, and February 28, 2018, and the postimplementation cohort included 144 patients admitted between July 29, 2019, and February 28, 2020.

Interventions

Implementation of a revised analgesia-sedation protocol.

Measurements and main results

Our primary outcome, total dose of IV midazolam administered in mechanical

SUBMITTER: Yang Y 

PROVIDER: S-EPMC8490269 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature