Sex Difference in the Relation Between Marital Status and Dementia Risk in Two Population-Based Cohorts.

ABSTRACT:

Background

The modifying effect of sex on the relation between marital status and dementia has yet to be determined.

Objective

To examine if sex modifies the association between marital status and incident dementia.

Methods

Population-based samples from the Mayo Clinic Study of Aging (MCSA, N = 3,471) and the Gothenburg H70 Birth Cohort Study (H70-study, N = 913) were used. A multiplicative interaction term was used to analyze the modifying effect of sex on the relation between marital status (married versus not married) and incident dementia using Cox regression models. Further, risk of dementia by marital status was also evaluated in models separated by sex.

Results

In the MCSA, there was an interaction between marital status and sex in relation to dementia (

SUBMITTER: Najar J 

PROVIDER: S-EPMC8490335 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature