Association Between Air Pollution and Lung Lobar Emphysema in COPD.

ABSTRACT: The development of emphysema has been linked to air pollution; however, the association of air pollution with the extent of lobar emphysema remains unclear. This study examined the association of particulate matter <2.5 μm in aerodynamic diameters (PM_2.5) (≤2.5 μm), nitrogen dioxide (NO₂), and ozone (O₃) level of exposure with the presence of emphysema in 86 patients with chronic obstructive pulmonary disease (COPD). Exposure to the air pollution estimated using the land-use regression model was associated with lung function, BODE (a body mass index, degree of obstruction, dyspnea severity, and exercise capacity index) quartiles, and emphysema measured as low-attenuation areas on high-resolution CT (HR-CT) lung scans. Using paraseptal emphysema as the refer

SUBMITTER: Tung NT 

PROVIDER: S-EPMC8490678 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature