Functional Characterization of a L-2-Haloacid Dehalogenase From Zobellia galactanivorans Dsij^T Suggests a Role in Haloacetic Acid Catabolism and a Wide Distribution in Marine Environments.

ABSTRACT: L-2-halocid dehalogenases (L-2-HADs) have been mainly characterized from terrestrial polluted environments. By contrast, knowledge is still scarce about their role in detoxification of predominant halocarbons in marine environments. Here, phylogenetic analyses showed a wide diversity of homologous L-2-HADs, especially among those belonging to marine bacteria. Previously characterized terrestrial L-2-HADs were part of a monophyletic group (named group A) including proteins of terrestrial and marine origin. Another branch (named group B) contained mostly marine L-2-HADs, with two distinct clades of Bacteroidetes homologs, closely linked to Proteobacteria ones. This study further focused on the characterization of the only L-2-HAD from the flavobacterium Zobellia galactanivor

SUBMITTER: Grigorian E 

PROVIDER: S-EPMC8490876 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature