Relationship between anaemia, coagulation parameters during pregnancy and postpartum haemorrhage at childbirth: a prospective cohort study.

ABSTRACT:

Objectives

To investigate the association between coagulation parameters and severity of anaemia (moderate anaemia: haemoglobin (Hb) 7-9.9 g/dL and severe anaemia: Hb <7 g/dL) during pregnancy and relate these to postpartum haemorrhage (PPH) at childbirth.

Design

A prospective cohort study of pregnant women recruited in the third trimester and followed-up after childbirth.

Setting

Ten hospitals across four states in India.

Participants

1342 pregnant women.

Intervention

Not applicable.

Methods

Hb and coagulation parameters: fibrinogen, D-dimer, D-dimer/fibrinogen ratio, platelets and international normalised ratio (INR) were measured at baseline. Participants were followed-up to measure blood loss within 2 hours after childbirth and PPH was defined

SUBMITTER: Nair M 

PROVIDER: S-EPMC8491293 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature