Generalizable cursor click decoding using grasp-related neural transients.

ABSTRACT: Objective.Intracortical brain-computer interfaces (iBCI) have the potential to restore independence for individuals with significant motor or communication impairments. One of the most realistic avenues for clinical translation of iBCI technology is enabling control of a computer cursor-i.e. movement-related neural activity is interpreted (decoded) and used to drive cursor function. Here we aim to improve cursor click decoding to allow for both point-and-click and click-and-drag control.Approach.Using chronic microelectrode arrays implanted in the motor cortex of two participants with tetraplegia, we identified prominent neural responses related to attempted hand grasp. We then developed a new approach for decoding cursor click (hand grasp) based on the most salient responses

SUBMITTER: Dekleva BM 

PROVIDER: S-EPMC8491307 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature