Validation of a derived version of the IPF-specific Saint George's Respiratory Questionnaire.

ABSTRACT:

Background

Health-related quality of life (HRQL) is impaired in patients with idiopathic pulmonary fibrosis (IPF). HRQL is often measured using the St. George's Respiratory Questionnaire (SGRQ) despite the development of an IPF-specific version (SGRQ-I). Using data from a real-world cohort of patients with IPF, we aimed to transform SGRQ into a derived version of SGRQ-I, SGRQ-I_der, to examine the cross-sectional and longitudinal validity of SGRQ-I_der and to compare SGRQ-I_der to SGRQ-I.

Methods

Based on results from SGRQ, SGRQ-I_der was derived applying the algorithm used to develop SGRQ-I. Of the 50 items in SGRQ, 34 items were retained in SGRQ-I_der. Response options for seven items were collapsed and minor adjustments we

SUBMITTER: Prior TS 

PROVIDER: S-EPMC8491388 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature