Ontology highlight
ABSTRACT:
SUBMITTER: Lou HY
PROVIDER: S-EPMC8491572 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Lou Hsin-Ya HY Zhao Wenting W Hanson Lindsey L Zeng Connie C Cui Yi Y Cui Bianxiao B
Langmuir : the ACS journal of surfaces and colloids 20170118 4
Clinical studies of circulating tumor cells (CTC) have stringent demands for high capture purity and high capture efficiency. Nanostructured surfaces have been shown to significantly increase the capture efficiency yet suffer from low capture purity. Here we introduce a dual-functional lipid coating on nanostructured surfaces. The lipid coating serves both as an effective passivation layer that helps prevent nonspecific cell adhesion and as a functionalized layer for antibody-based specific cell ...[more]