Whole-Brain Functional Dynamics Track Depressive Symptom Severity.

ABSTRACT: Depressive symptoms are reported by 20% of the population and are related to altered functional integrity of large-scale brain networks. The link between moment-to-moment brain function and depressive symptomatology, and the implications of these relationships for clinical and community populations alike, remain understudied. The present study examined relationships between functional brain dynamics and subclinical-to-mild depressive symptomatology in a large community sample of adults with and without psychiatric diagnoses. This study used data made available through the Enhanced Nathan Kline Institute-Rockland Sample; 445 participants between 18 and 65 years of age completed a 10-min resting-state functional MRI scan. Coactivation pattern analysis was used to examine the dimensional rela

SUBMITTER: Goodman ZT 

PROVIDER: S-EPMC8491671 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature